Microfluidic Magnetic Separation Device

Background:

 

For my senior project, I was part of a team that developed a microfluidic magnetic separation device.The device was fabricated in PDMS, and used a H filter geometry to separate magnetic beads from non magnetic beads. Two inlet streams were run through one channel, creating a boundary layer which the magnetic beads were pulled across in order to separate them from non-magnetic beads. 

 

My Contribution:

 

I analyzed the design in order to optimize the dimensions of the fluidic channel and the amount of magnetic force needed for separation. I used COMSOL to investigate the fluid flow optimize inlet and outlet pressures. I wrote a simulation in MATLAB to simulate the distance traveled by magnetic beads as they moved down the length of the channel. 

 

•COMSOL simulations

•MatLab 

•Soft Lithography